This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

DOID Endpoint Browser

Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS

No definition available.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Z80-Z99 Cause of death: ICD-10 — Z80-Z99 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints Z21_FAMILY_HISTORY_MALIG_NEOPLASM Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL Z21_FAMILY_HISTORY_OTH_SPECIFIC_DISORD Z21_FAMILY_HISTORY_OTH_CONDI Z21_PERSONAL_HISTORY_MALIG_NEOPLASM Z21_PERSONAL_HISTORY_CERTA_OTH_DISEA Z21_PERSONAL_HISTORY_OTH_DISEA_CONDI Z21_PERSONAL_HISTORY_ALLERGY_DRUGS_MEDICAM_BIOLO_SUBST Z21_ACQUI_ABSENCE_LIMB Z21_ACQUI_ABSENCE_ORGANS_NOT_ELSEW_CLASSIFIED Z21_PERSONAL_HISTORY_RISK__NOT_ELSEW_CLASSIFIED Z21_PERSONAL_HISTORY_MEDICAL_TREAT Z21_ARTIF_OPENI_STATUS Z21_TRANSPLANTED_ORGAN_TISSUE_STATUS Z21_PRESENCE_CARDIAC_VASCULAR_IMPLANTNTS_GRAFTS Z21_PRESENCE_OTH_FUNCTIONAL_IMPLANTNTS Z21_PRESENCE_OTH_DEVICES Z21_OTHER_POSTS_STATES Z21_DEPENDENCE_ENABL_MACHINES_DEVICES_NOT_ELSEW_CLASSIFIED	63063
6. Filter based on genotype QC (FinnGen only)	60919

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Z

NAME	Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	Z21_FAMILY_HISTORY_MALIG_NEOPLASM\|Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD\|Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL\|Z21_FAMILY_HISTORY_OTH_SPECIFIC_DISORD\|Z21_FAMILY_HISTORY_OTH_CONDI\|Z21_PERSONAL_HISTORY_MALIG_NEOPLASM\|Z21_PERSONAL_HISTORY_CERTA_OTH_DISEA\|Z21_PERSONAL_HISTORY_OTH_DISEA_CONDI\|Z21_PERSONAL_HISTORY_ALLERGY_DRUGS_MEDICAM_BIOLO_SUBST\|Z21_ACQUI_ABSENCE_LIMB\|Z21_ACQUI_ABSENCE_ORGANS_NOT_ELSEW_CLASSIFIED\|Z21_PERSONAL_HISTORY_RISK__NOT_ELSEW_CLASSIFIED\|Z21_PERSONAL_HISTORY_MEDICAL_TREAT\|Z21_ARTIF_OPENI_STATUS\|Z21_TRANSPLANTED_ORGAN_TISSUE_STATUS\|Z21_PRESENCE_CARDIAC_VASCULAR_IMPLANTNTS_GRAFTS\|Z21_PRESENCE_OTH_FUNCTIONAL_IMPLANTNTS\|Z21_PRESENCE_OTH_DEVICES\|Z21_OTHER_POSTS_STATES\|Z21_DEPENDENCE_ENABL_MACHINES_DEVICES_NOT_ELSEW_CLASSIFIED
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Z[8-9]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Z[8-9]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Persons with potential health hazards related to family and personal history and certain conditions influencing health status based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	60919	31172	29747
Unadjusted period prevalence (%)	14.92	13.54	16.36
Median age at first event (years)	66.55	64.45	68.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS – Persons with potential health hazards related to family and personal history and certain conditions influencing health status

GWS hits: -

Loading Relationships table

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints