Ulcerative enterocolitis

ULCERENTER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.0
  • Cause of death: ICD-10 K51.0

2 out of 7 registries used, show all original rules.

1040

4. Check minimum number of events

None

1040

5. Include endpoints

None

1040

6. Filter based on genotype QC (FinnGen only)

1010

Control definitions (FinnGen only)

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Enterocolitis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7478 3539 3905
Only index persons 6872 3325 3547
Unadjusted period prevalence (%)
Whole population 0.11 0.10 0.11
Only index persons 0.13 0.12 0.14
Median age at first event (years)
Whole population 43.87 41.69 45.68
Only index persons 42.10 40.37 43.72

-FinnGen-

Key figures

All Female Male
Number of individuals 1010 538 472
Unadjusted period prevalence (%) 0.25 0.23 0.26
Median age at first event (years) 42.37 36.87 48.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ULCERENTER – Ulcerative enterocolitis

GWS hits: 3

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