Spondyloarthritis

SPONDYLOARTHRITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M45, M45+H22.1, M45+J99.8, M46
  • Hospital discharge: ICD-9 720
  • Hospital discharge: ICD-8 7124|7131|72699
  • Cause of death: ICD-10 M45, M45+H22.1, M45+J99.8, M46
  • Cause of death: ICD-9 720
  • Cause of death: ICD-8 7124|7131|72699

2 out of 7 registries used, show all original rules.

7235

4. Check minimum number of events

None

7235

5. Include endpoints

None

7235

6. Filter based on genotype QC (FinnGen only)

6991

Control definitions (FinnGen only)

Control exclude ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 77792 37939 38710
Only index persons 54653 28037 26616
Unadjusted period prevalence (%)
Whole population 1.09 1.09 1.08
Only index persons 1.02 1.03 1.02
Median age at first event (years)
Whole population 50.27 50.96 49.42
Only index persons 44.82 46.02 43.55

-FinnGen-

Key figures

All Female Male
Number of individuals 6991 3498 3493
Unadjusted period prevalence (%) 1.72 1.52 1.92
Median age at first event (years) 44.84 42.59 47.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: SPONDYLOARTHRITIS – Spondyloarthritis

GWS hits: 11

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