Biological medication for rheuma

RX_RHEUMA_BIOLOGICAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC L04AA24|L04AC03|L04AB04|L04AB01|L04AB06|L04AB02|L04AB05|L04AA26|L01XC02|L04AC10|L04AC07|L04AC05

1 out of 7 registries used, show all original rules.

5294

4. Check minimum number of events

Min. number of events 3
5294

5. Include endpoints

None

5294

6. Filter based on genotype QC (FinnGen only)

5117

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 27308 15324 11931
Only index persons 26669 14962 11707
Unadjusted period prevalence (%)
Whole population 0.39 0.44 0.33
Only index persons 0.50 0.55 0.45
Median age at first event (years)
Whole population 45.20 45.96 44.26
Only index persons 45.68 46.51 44.62

-FinnGen-

Key figures

All Female Male
Number of individuals 5117 3157 1960
Unadjusted period prevalence (%) 1.26 1.37 1.08
Median age at first event (years) 48.47 48.50 48.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RX_RHEUMA_BIOLOGICAL – Biological medication for rheuma

GWS hits: 4

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