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Tumor necrosis factor alpha inhibitors

RX_L04AB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC L04AB

1 out of 7 registries used, show all original rules.

4749

4. Check minimum number of events

Min. number of events 3
4749

5. Include endpoints

4749

6. Filter based on genotype QC (FinnGen only)

4591

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 4591 2870 1721
Unadjusted period prevalence (%) 1.13 1.25 0.95
Median age at first event (years) 47.70 47.64 47.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: RX_L04AB – Tumor necrosis factor alpha inhibitors

GWS hits: -

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