≡ Risteys
FR+FG R10

Documentation Changelog GitHub Contact & Feedback

Other/unspecified rheumatoid arthritis

DOID EFO Endpoint Browser PheWeb

RHEUMA_NOS

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M06.8, M06.9
  • Hospital discharge: ICD-9 — 7148
  • Hospital discharge: ICD-8 — 7123[8-9]
  • Cause of death: ICD-10 — M06.8, M06.9
  • Cause of death: ICD-9 — 7148
  • Cause of death: ICD-8 — 7123[8-9]

2 out of 7 registries used, show all original rules.

4320

4. Check minimum number of events

None

4320

5. Include endpoints

None

4320

6. Filter based on genotype QC (FinnGen only)

4216

Control definitions (FinnGen only)

Control exclude STILL_ADULT

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 51998 36359 14963
Only index persons 33687 24467 9220
Unadjusted period prevalence (%)
Whole population 0.86 1.04 0.42
Only index persons 0.75 0.90 0.35
Median age at first event (years)
Whole population 56.20 55.97 56.80
Only index persons 53.67 53.16 55.03

-FinnGen-

Key figures

All Female Male
Number of individuals 4216 2813 1403
Unadjusted period prevalence (%) 1.07 1.22 0.77
Median age at first event (years) 49.76 47.63 54.02

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Relationships between endpoints

↥

Index endpoint: RHEUMA_NOS – Other/unspecified rheumatoid arthritis

GWS hits: 5

loading spinner Loading Relationships table