kidney failure: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. [ NCIT:P378 ]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
16042 |
6. Filter based on genotype QC (FinnGen only) |
15475 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Renal failure
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 167529 | 73792 | 92048 |
| Only index persons | 136104 | 60579 | 75525 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.36 | 2.11 | 2.57 |
| Only index persons | 2.59 | 2.23 | 2.88 |
| Median age at first event (years) | |||
| Whole population | 76.09 | 79.57 | 73.34 |
| Only index persons | 76.22 | 79.93 | 73.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 15475 | 5256 | 10219 |
| Unadjusted period prevalence (%) | 4.49 | 2.28 | 5.62 |
| Median age at first event (years) | 70.99 | 69.55 | 71.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: N14_RENFAIL – Renal failure
GWS hits: 5
Loading Relationships table