Acute renal failure

N14_ACUTERENFAIL

kidney failure: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. [ NCIT:P378 ]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N17
  • Hospital discharge: ICD-9 584
  • Cause of death: ICD-10 N17
  • Cause of death: ICD-9 584

2 out of 7 registries used, show all original rules.

6654

4. Check minimum number of events

None

6654

5. Include endpoints

None

6654

6. Filter based on genotype QC (FinnGen only)

6429

Control definitions (FinnGen only)

Control exclude N14_RENFAIL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N17-N19
Name in latin Insufficientia renalis acuta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 70474 30883 38957
Only index persons 58723 25895 32828
Unadjusted period prevalence (%)
Whole population 1.00 0.88 1.09
Only index persons 1.12 0.95 1.25
Median age at first event (years)
Whole population 73.61 77.58 70.45
Only index persons 73.20 77.27 69.99

-FinnGen-

Key figures

All Female Male
Number of individuals 6429 2273 4156
Unadjusted period prevalence (%) 1.83 0.99 2.29
Median age at first event (years) 69.90 69.46 70.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: N14_ACUTERENFAIL – Acute renal failure

GWS hits: 1

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