All dysplastic lesions of the cervix uteri, vagina or vulva

N14_FEMALE_GENITAL_DYSPLASIA_ALL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N87|N89[0-3]|N90[0-3]|D06|D071|D072
  • Hospital discharge: ICD-9 6221A|6221B|6221C|0781C|2331A|2333A|6230B|6230C|2333B
  • Cause of death: ICD-10 N87|N89[0-3]|N90[0-3]|D06|D071|D072
  • Cause of death: ICD-9 6221A|6221B|6221C|0781C|2331A|2333A|6230B|6230C|2333B

2 out of 7 registries used, show all original rules.

10661

4. Check minimum number of events

None

10661

5. Include endpoints

None

10661

6. Filter based on genotype QC (FinnGen only)

10251

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 86287 86287 -
Only index persons 84042 84042 -
Unadjusted period prevalence (%)
Whole population 2.47 2.47 -
Only index persons 3.09 3.09 -
Median age at first event (years)
Whole population - 35.10 -
Only index persons - 34.95 -

-FinnGen-

Key figures

All Female Male
Number of individuals 10251 10251 -
Unadjusted period prevalence (%) 4.45 4.45 -
Median age at first event (years) 35.59 35.59 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: N14_FEMALE_GENITAL_DYSPLASIA_ALL – All dysplastic lesions of the cervix uteri, vagina or vulva

GWS hits: 2

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