HSIL lesion of the cervix uteri

N14_CERVICAL_HSIL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06, N87.1, N87.2
  • Hospital discharge: ICD-9 6221B|6221C|2331A
  • Cause of death: ICD-10 D06, N87.1, N87.2
  • Cause of death: ICD-9 6221B|6221C|2331A

2 out of 7 registries used, show all original rules.

6360

4. Check minimum number of events

None

6360

5. Include endpoints

None

6360

6. Filter based on genotype QC (FinnGen only)

6088

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

List of similar endpoints to HSIL lesion of the cervix uteri based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 53171 53171 -
Only index persons 51989 51989 -
Unadjusted period prevalence (%)
Whole population 1.52 1.52 -
Only index persons 1.91 1.91 -
Median age at first event (years)
Whole population - 34.59 -
Only index persons - 34.40 -

-FinnGen-

Key figures

All Female Male
Number of individuals 6088 6088 -
Unadjusted period prevalence (%) 2.64 2.64 -
Median age at first event (years) 35.04 35.04 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: N14_CERVICAL_HSIL – HSIL lesion of the cervix uteri

GWS hits: 4

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