Migraine, single triptan purchase ok & required. ICD-code if available is included

MIGRAINE_TRIPTAN

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • TRIPTAN1
46305

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

46305

6. Filter based on genotype QC (FinnGen only)

44615

Control definitions (FinnGen only)

Control conditions not TRIPTAN1

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 389861 295751 91867
Only index persons 381814 291805 90009
Unadjusted period prevalence (%)
Whole population 7.04 8.47 2.57
Only index persons 9.01 10.73 3.44
Median age at first event (years)
Whole population 33.66 33.62 33.77
Only index persons 33.61 33.57 33.72

-FinnGen-

Key figures

All Female Male
Number of individuals 44615 37287 7328
Unadjusted period prevalence (%) 14.19 16.19 4.03
Median age at first event (years) 36.67 35.97 40.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: MIGRAINE_TRIPTAN – Migraine, single triptan purchase ok & required. ICD-code if available is included

GWS hits: 43

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