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Spondylosis

DOID EFO Endpoint Browser PheWeb

M13_SPONDYLOSIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M47
  • Hospital discharge: ICD-9 — 721[0-4]
  • Cause of death: ICD-10 — M47
  • Cause of death: ICD-9 — 721[0-4]

2 out of 7 registries used, show all original rules.

22543

4. Check minimum number of events

None

22543

5. Include endpoints

None

22543

6. Filter based on genotype QC (FinnGen only)

21876

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M45-M49
Name in latin Spondylosis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 176743 94465 81168
Only index persons 157735 86592 71143
Unadjusted period prevalence (%)
Whole population 2.49 2.71 2.27
Only index persons 2.97 3.18 2.72
Median age at first event (years)
Whole population 59.47 60.41 58.26
Only index persons 58.23 59.23 57.00

-FinnGen-

Key figures

All Female Male
Number of individuals 21876 12193 9683
Unadjusted period prevalence (%) 5.31 5.29 5.33
Median age at first event (years) 58.24 57.53 59.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_SPONDYLOSIS – Spondylosis

GWS hits: 8

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