Spondylopathies in diseases classified elsewhere

M13_SPONDYLOPATHINOTH

spondyloarthropathy: A group of inflammatory rheumatic diseases associated with arthritis and enthesitis, and often involving the axial skeleton. The most common form of spondyloarthritis is ankylosing spondylitis. Other forms include axial spondyloarthritis, peripheral spondyloarthritis, reactive arthritis, psoriatic arthritis/spondylitis and enteropathic arthritis/spondylitis.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M49*
  • Cause of death: ICD-10 M49*

2 out of 7 registries used, show all original rules.

338

4. Check minimum number of events

None

338

5. Include endpoints

None

338

6. Filter based on genotype QC (FinnGen only)

319

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2934 1388 1517
Only index persons 2404 1175 1229
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.05 0.04 0.05
Median age at first event (years)
Whole population 67.32 67.49 67.19
Only index persons 67.27 67.47 67.08

-FinnGen-

Key figures

All Female Male
Number of individuals 319 138 181
Unadjusted period prevalence (%) 0.08 0.06 0.10
Median age at first event (years) 67.64 65.06 69.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_SPONDYLOPATHINOTH – Spondylopathies in diseases classified elsewhere

GWS hits: -

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