Thrombotic microangiopathy

M13_HTROMBMICROANG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M31.1
  • Hospital discharge: ICD-9 4466
  • Hospital discharge: ICD-8 4464
  • Cause of death: ICD-10 M31.1
  • Cause of death: ICD-9 4466
  • Cause of death: ICD-8 4464

2 out of 7 registries used, show all original rules.

180

4. Check minimum number of events

None

180

5. Include endpoints

None

180

6. Filter based on genotype QC (FinnGen only)

174

Control definitions (FinnGen only)

Control exclude M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Microangiopathia thrombotica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1214 706 498
Only index persons 1034 606 428
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 56.61 55.13 58.60
Only index persons 55.82 54.53 57.64

-FinnGen-

Key figures

All Female Male
Number of individuals 174 98 76
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 54.21 52.08 56.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: M13_HTROMBMICROANG – Thrombotic microangiopathy

GWS hits: -

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