De Quervain disease: Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1797 |
4. Check minimum number of eventsNone |
1797 |
5. Include endpointsNone |
1797 |
6. Filter based on genotype QC (FinnGen only) |
1734 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Tenosynovitis regionis processus styloidis radii (de Quervain)
Similar endpoints
↥List of similar endpoints to
Radial styloid tenosynovitis [de Quervain]
based on the number of shared cases.
Broader endpoints:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12769 | 9682 | 3012 |
| Only index persons | 12386 | 9470 | 2916 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.23 | 0.28 | 0.08 |
| Only index persons | 0.29 | 0.35 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 45.91 | 47.16 | 42.00 |
| Only index persons | 45.71 | 46.93 | 41.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1734 | 1411 | 323 |
| Unadjusted period prevalence (%) | 0.53 | 0.61 | 0.18 |
| Median age at first event (years) | 47.91 | 47.60 | 49.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_DEQUERVAIN – Radial styloid tenosynovitis [de Quervain]
GWS hits: 2
Loading Relationships table