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Vitiligo

DOID EFO Endpoint Browser PheWeb

L12_VITILIGO

Vitiligo: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L80
  • Hospital discharge: ICD-9 — 7090F
  • Hospital discharge: ICD-8 — 70905
  • Cause of death: ICD-10 — L80
  • Cause of death: ICD-9 — 7090F
  • Cause of death: ICD-8 — 70905

2 out of 7 registries used, show all original rules.

307

4. Check minimum number of events

None

307

5. Include endpoints

None

307

6. Filter based on genotype QC (FinnGen only)

292

Control definitions (FinnGen only)

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Vitiligo

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3372 1868 1488
Only index persons 3076 1720 1356
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.04
Only index persons 0.06 0.06 0.05
Median age at first event (years)
Whole population 36.14 37.31 34.62
Only index persons 36.81 38.02 35.29

-FinnGen-

Key figures

All Female Male
Number of individuals 292 174 118
Unadjusted period prevalence (%) 0.07 0.08 0.06
Median age at first event (years) 46.47 43.92 50.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_VITILIGO – Vitiligo

GWS hits: -

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