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Other and unspecified acute skin changes due to ultraviolet radiation

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L12_OTHACUSKINSUNNAS

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L56.8, L56.9
  • Hospital discharge: ICD-9 — 6927
  • Hospital discharge: ICD-8 — 6928
  • Hospital discharge: excluded ICD-9 — 6927F
  • Cause of death: ICD-10 — L56.8, L56.9
  • Cause of death: ICD-9 — 6927
  • Cause of death: ICD-8 — 6928
  • Cause of death: excluded ICD-9 — 6927F

2 out of 7 registries used, show all original rules.

800

4. Check minimum number of events

None

800

5. Include endpoints

None

800

6. Filter based on genotype QC (FinnGen only)

782

Control definitions (FinnGen only)

Control exclude L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9789 4557 5076
Only index persons 6433 3241 3192
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.14
Only index persons 0.12 0.12 0.12
Median age at first event (years)
Whole population 44.43 47.31 41.57
Only index persons 35.57 39.46 31.63

-FinnGen-

Key figures

All Female Male
Number of individuals 782 336 446
Unadjusted period prevalence (%) 0.20 0.15 0.25
Median age at first event (years) 37.94 37.17 38.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_OTHACUSKINSUNNAS – Other and unspecified acute skin changes due to ultraviolet radiation

GWS hits: -

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