Other acute skin changes due to ultraviolet radiation

L12_OTHACUSKINSUN

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L56
  • Cause of death: ICD-10 L56

2 out of 7 registries used, show all original rules.

511

4. Check minimum number of events

None

511

5. Include endpoints

1099

6. Filter based on genotype QC (FinnGen only)

1073

Control definitions (FinnGen only)

Control exclude L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L55-L59
Name in latin Aliae commutationes acutae cutis e radiatione ultraviolacea

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12305 6288 5855
Only index persons 8709 4853 3856
Unadjusted period prevalence (%)
Whole population 0.17 0.18 0.16
Only index persons 0.16 0.18 0.15
Median age at first event (years)
Whole population 44.15 46.17 41.73
Only index persons 37.54 41.00 33.18

-FinnGen-

Key figures

All Female Male
Number of individuals 1073 559 514
Unadjusted period prevalence (%) 0.26 0.24 0.28
Median age at first event (years) 40.89 40.83 40.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: L12_OTHACUSKINSUN – Other acute skin changes due to ultraviolet radiation

GWS hits: 1

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