Lichen simplex chronicus and prurigo

L12_LICHSIMPANDPRURIGO

neurodermatitis: an itchy skin disease similar to atopic dermatitis. It tends to result in focal patches—one or many—that are due to frequent rubbing or scratching of the same area over time.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L28
  • Cause of death: ICD-10 L28

2 out of 7 registries used, show all original rules.

1847

4. Check minimum number of events

None

1847

5. Include endpoints

1939

6. Filter based on genotype QC (FinnGen only)

1879

Control definitions (FinnGen only)

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Neurodermatitis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17097 9353 7639
Only index persons 15358 8556 6802
Unadjusted period prevalence (%)
Whole population 0.24 0.27 0.21
Only index persons 0.29 0.31 0.26
Median age at first event (years)
Whole population 56.19 56.86 55.37
Only index persons 55.35 55.98 54.56

-FinnGen-

Key figures

All Female Male
Number of individuals 1879 1072 807
Unadjusted period prevalence (%) 0.46 0.47 0.44
Median age at first event (years) 56.18 54.98 57.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: L12_LICHSIMPANDPRURIGO – Lichen simplex chronicus and prurigo

GWS hits: 2

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