lichen disease: a long-term skin condition that mainly affects the skin of the genitals. It usually causes itching and white patches to appear on the affected skin.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 
 2 out of 7 registries used, show all original rules.  | 
							
								 1030  | 
						
								4. Check minimum number of eventsNone  | 
							1030 | 
								5. Include endpointsNone  | 
							1030 | 
										6. Filter based on genotype QC (FinnGen only) | 
									992 | 
Control definitions (FinnGen only)
					Control exclude
					L12_DERMATITISECZEMA
				
			Extra metadata
					Level in the ICD hierarchy
					4
				
				
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					L28
				
				
					Name in latin
					Lichen simplex chronicus
				
			Similar endpoints
↥List of similar endpoints to
		
Lichen simplex chronicus
	based on the number of shared cases.
		
		Broader endpoints:
	
- Lichen simplex chronicus and prurigo
 - Dermatitis and eczema
 - Diseases of the skin and subcutaneous tissue
 - Any event in hilmo or specialist outpatient
 
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8813 | 4491 | 4275 | 
| Only index persons | 7913 | 4095 | 3818 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.12 | 
| Only index persons | 0.15 | 0.15 | 0.15 | 
| Median age at first event (years) | |||
| Whole population | 53.53 | 54.18 | 52.91 | 
| Only index persons | 52.84 | 53.38 | 52.26 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 992 | 537 | 455 | 
| Unadjusted period prevalence (%) | 0.24 | 0.23 | 0.25 | 
| Median age at first event (years) | 53.07 | 51.88 | 54.48 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: L12_LICHENSIMPLEX – Lichen simplex chronicus
GWS hits: 2
                
                Loading Relationships table