Lichen simplex chronicus

L12_LICHENSIMPLEX

lichen disease: a long-term skin condition that mainly affects the skin of the genitals. It usually causes itching and white patches to appear on the affected skin.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L28.0
  • Hospital discharge: ICD-9 6983B|697X
  • Hospital discharge: ICD-8 6983
  • Cause of death: ICD-10 L28.0
  • Cause of death: ICD-9 6983B|697X
  • Cause of death: ICD-8 6983

2 out of 7 registries used, show all original rules.

1030

4. Check minimum number of events

None

1030

5. Include endpoints

None

1030

6. Filter based on genotype QC (FinnGen only)

992

Control definitions (FinnGen only)

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L28
Name in latin Lichen simplex chronicus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8813 4491 4275
Only index persons 7913 4095 3818
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.12
Only index persons 0.15 0.15 0.15
Median age at first event (years)
Whole population 53.53 54.18 52.91
Only index persons 52.84 53.38 52.26

-FinnGen-

Key figures

All Female Male
Number of individuals 992 537 455
Unadjusted period prevalence (%) 0.24 0.23 0.25
Median age at first event (years) 53.07 51.88 54.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: L12_LICHENSIMPLEX – Lichen simplex chronicus

GWS hits: 2

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