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Lichen sclerosus et atrophicus

EFO MESH Endpoint Browser PheWeb

L12_LICHENSCLERATROPH

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L90.0
  • Hospital discharge: ICD-9 — 7010
  • Hospital discharge: ICD-8 — 70101
  • Cause of death: ICD-10 — L90.0
  • Cause of death: ICD-9 — 7010
  • Cause of death: ICD-8 — 70101

2 out of 7 registries used, show all original rules.

2829

4. Check minimum number of events

None

2829

5. Include endpoints

None

2829

6. Filter based on genotype QC (FinnGen only)

2755

Control definitions (FinnGen only)

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L90
Name in latin Lichen sclerosus et atrophicus

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 21817 18224 3552
Only index persons 21007 17541 3466
Unadjusted period prevalence (%)
Whole population 0.45 0.52 0.10
Only index persons 0.56 0.64 0.13
Median age at first event (years)
Whole population 60.38 64.39 39.87
Only index persons 60.31 64.36 39.85

-FinnGen-

Key figures

All Female Male
Number of individuals 2755 2387 368
Unadjusted period prevalence (%) 0.93 1.04 0.20
Median age at first event (years) 61.97 63.42 52.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_LICHENSCLERATROPH – Lichen sclerosus et atrophicus

GWS hits: 1

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