Speech and linguistic disorders (more control exclusions)

KRA_PSY_SPEELING_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F80, F81
  • Hospital discharge: ICD-9 315[0-3]|3159
  • Hospital discharge: ICD-8 31610
  • Cause of death: ICD-10 F80, F81
  • Cause of death: ICD-9 315[0-3]|3159
  • Cause of death: ICD-8 31610

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 97743 31956 65733
Only index persons 79113 26544 52569
Unadjusted period prevalence (%)
Whole population 1.53 0.92 1.84
Only index persons 1.66 0.98 2.01
Median age at first event (years)
Whole population 6.89 7.95 6.36
Only index persons 7.77 9.26 7.02

-FinnGen-

Key figures

All Female Male
Number of individuals 2874 1418 1456
Unadjusted period prevalence (%) 0.71 0.62 0.80
Median age at first event (years) 10.68 12.96 8.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: KRA_PSY_SPEELING_EXMORE – Speech and linguistic disorders (more control exclusions)

GWS hits: 1

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