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Personality disorders (more control exclusions)

Endpoint Browser PheWeb

KRA_PSY_PERSON_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60, F61
  • Hospital discharge: ICD-9 — 31[0|2|4]|315A|31[6-8]
  • Hospital discharge: ICD-8 — 30100|301[2-9]
  • Cause of death: ICD-10 — F60, F61
  • Cause of death: ICD-9 — 31[0|2|4]|315A|31[6-8]
  • Cause of death: ICD-8 — 30100|301[2-9]

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

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Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 118192 61352 55922
Only index persons 104272 56926 47346
Unadjusted period prevalence (%)
Whole population 1.66 1.76 1.56
Only index persons 1.96 2.09 1.81
Median age at first event (years)
Whole population 31.56 32.06 30.92
Only index persons 30.95 31.47 30.32

-FinnGen-

Key figures

All Female Male
Number of individuals 10893 6889 4004
Unadjusted period prevalence (%) 2.70 2.99 2.20
Median age at first event (years) 33.04 32.66 33.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: KRA_PSY_PERSON_EXMORE – Personality disorders (more control exclusions)

GWS hits: 2

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