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Wide developmental disorders (more control exclusions)

Endpoint Browser PheWeb

KRA_PSY_DEVWIDE_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F84
  • Hospital discharge: ICD-9 — 299[0|8|9]
  • Cause of death: ICD-10 — F84
  • Cause of death: ICD-9 — 299[0|8|9]

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F80-F89
Name in latin Perturbationes formationales pervasivae (in pueritia)

Case counts by codes

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FinnGen case counts by registry codes:

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No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29615 8508 21079
Only index persons 24625 7408 17217
Unadjusted period prevalence (%)
Whole population 0.49 0.24 0.59
Only index persons 0.54 0.27 0.66
Median age at first event (years)
Whole population 11.12 14.02 9.93
Only index persons 12.43 15.02 11.32

-FinnGen-

Key figures

All Female Male
Number of individuals 861 365 496
Unadjusted period prevalence (%) 0.22 0.16 0.27
Median age at first event (years) 18.92 21.33 17.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: KRA_PSY_DEVWIDE_EXMORE – Wide developmental disorders (more control exclusions)

GWS hits: 1

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