Molar incisor enamel hypoplasia, with caries

K11_MIH_CARIES

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • K11_CARIES
10174

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

214

4. Check minimum number of events

None

214

5. Include endpoints

214

6. Filter based on genotype QC (FinnGen only)

193

Control definitions (FinnGen only)

Control conditions not K11_CARIES

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2382 1118 1261
Only index persons 1584 754 830
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.04
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 8.86 8.93 8.74
Only index persons 11.23 11.43 11.04

-FinnGen-

Key figures

All Female Male
Number of individuals 193 99 94
Unadjusted period prevalence (%) 0.05 0.04 0.05
Median age at first event (years) 8.24 8.84 7.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_MIH_CARIES – Molar incisor enamel hypoplasia, with caries

GWS hits: 1

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