Molar incisor enamel hypoplasia

K11_MIH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

727

4. Check minimum number of events

None

727

5. Include endpoints

727

6. Filter based on genotype QC (FinnGen only)

676

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26829 14582 12214
Only index persons 19103 10748 8355
Unadjusted period prevalence (%)
Whole population 0.38 0.42 0.34
Only index persons 0.36 0.40 0.32
Median age at first event (years)
Whole population 10.94 11.50 10.22
Only index persons 13.36 13.99 12.56

-FinnGen-

Key figures

All Female Male
Number of individuals 676 455 221
Unadjusted period prevalence (%) 0.17 0.20 0.12
Median age at first event (years) 16.65 19.17 11.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: K11_MIH – Molar incisor enamel hypoplasia

GWS hits: 1

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