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Chronic pancreatitis

DOID EFO Endpoint Browser PheWeb

K11_CHRONPANC

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K86.00, K86.01, K86.08, K86.1
  • Hospital discharge: ICD-9 — 5771
  • Hospital discharge: ICD-8 — 5771
  • Cause of death: ICD-10 — K86.00, K86.01, K86.08, K86.1
  • Cause of death: ICD-9 — 5771
  • Cause of death: ICD-8 — 5771
  • KELA reimbursements: KELA codes — 133

3 out of 7 registries used, show all original rules.

3983

4. Check minimum number of events

None

3983

5. Include endpoints

None

3983

6. Filter based on genotype QC (FinnGen only)

3875

Control definitions (FinnGen only)

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 41461 11321 29733
Only index persons 32317 9387 22930
Unadjusted period prevalence (%)
Whole population 0.69 0.32 0.83
Only index persons 0.72 0.35 0.88
Median age at first event (years)
Whole population 53.49 58.70 51.48
Only index persons 53.93 58.91 51.89

-FinnGen-

Key figures

All Female Male
Number of individuals 3875 1252 2623
Unadjusted period prevalence (%) 1.15 0.54 1.44
Median age at first event (years) 56.81 58.42 56.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: K11_CHRONPANC – Chronic pancreatitis

GWS hits: 5

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