Alcohol-induced chronic pancreatitis

ALCOPANCCHRON

alcoholic pancreatitis: Acute or chronic inflammation of the pancreas due to excessive alcohol drinking. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K86.00, K86.01, K86.08
  • Hospital discharge: ICD-9 5771C|5771D
  • Cause of death: ICD-10 K86.00, K86.01, K86.08
  • Cause of death: ICD-9 5771C|5771D

2 out of 7 registries used, show all original rules.

2008

4. Check minimum number of events

None

2008

5. Include endpoints

None

2008

6. Filter based on genotype QC (FinnGen only)

1959

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26565 4781 21551
Only index persons 20455 3883 16572
Unadjusted period prevalence (%)
Whole population 0.52 0.14 0.60
Only index persons 0.54 0.14 0.63
Median age at first event (years)
Whole population 49.32 50.76 48.95
Only index persons 49.19 50.78 48.82

-FinnGen-

Key figures

All Female Male
Number of individuals 1959 427 1532
Unadjusted period prevalence (%) 0.70 0.19 0.84
Median age at first event (years) 50.70 49.78 50.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ALCOPANCCHRON – Alcohol-induced chronic pancreatitis

GWS hits: 4

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