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Acute appendicitis

DOID EFO Endpoint Browser PheWeb

K11_APPENDACUT

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K35
  • Hospital discharge: ICD-9 — 540
  • Hospital discharge: ICD-8 — 540
  • Cause of death: ICD-10 — K35
  • Cause of death: ICD-9 — 540
  • Cause of death: ICD-8 — 540

2 out of 7 registries used, show all original rules.

32585

4. Check minimum number of events

None

32585

5. Include endpoints

None

32585

6. Filter based on genotype QC (FinnGen only)

31628

Control definitions (FinnGen only)

Control exclude K11_APPENDIX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K35-K38
Name in latin Appendicitis acuta

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 338518 157317 179425
Only index persons 312186 147834 164352
Unadjusted period prevalence (%)
Whole population 4.76 4.51 5.01
Only index persons 5.88 5.43 6.27
Median age at first event (years)
Whole population 29.24 28.86 29.42
Only index persons 28.24 28.11 28.36

-FinnGen-

Key figures

All Female Male
Number of individuals 31628 17142 14486
Unadjusted period prevalence (%) 7.68 7.44 7.97
Median age at first event (years) 31.68 29.20 34.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: K11_APPENDACUT – Acute appendicitis

GWS hits: 22

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