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Acute appendicitis, with complications

DOID EFO Endpoint Browser PheWeb

APPENDACUT_COMPLIC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K35.0, K35.1
  • Hospital discharge: ICD-9 — 540[0-1]
  • Hospital discharge: ICD-8 — 540
  • Hospital discharge: excluded ICD-8 — 54090|54099
  • Cause of death: ICD-10 — K35.0, K35.1
  • Cause of death: ICD-9 — 540[0-1]
  • Cause of death: ICD-8 — 540
  • Cause of death: excluded ICD-8 — 54090|54099

2 out of 7 registries used, show all original rules.

7572

4. Check minimum number of events

None

7572

5. Include endpoints

None

7572

6. Filter based on genotype QC (FinnGen only)

7358

Control definitions (FinnGen only)

Control exclude K11_APPENDIX

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 84045 36878 46560
Only index persons 72602 32822 39780
Unadjusted period prevalence (%)
Whole population 1.19 1.06 1.30
Only index persons 1.38 1.21 1.52
Median age at first event (years)
Whole population 33.29 33.34 32.99
Only index persons 30.31 30.74 29.95

-FinnGen-

Key figures

All Female Male
Number of individuals 7358 3511 3847
Unadjusted period prevalence (%) 1.83 1.52 2.12
Median age at first event (years) 33.94 30.64 36.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications

GWS hits: 5

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