interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
4710 |
6. Filter based on genotype QC (FinnGen only) |
4572 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Interstitial lung disease endpoints
based on the number of shared cases.
Broader endpoints:
- Other interstitial pulmonary diseases
- Interstitial lung disease
- Respiratory diseases principally affecting the interstitium, IBD co-morbidites
- Other respiratory diseases principally affecting the interstitium
- Diseases of the respiratory system
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 38350 | 16182 | 21649 |
| Only index persons | 27651 | 12043 | 15608 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.54 | 0.46 | 0.60 |
| Only index persons | 0.53 | 0.44 | 0.60 |
| Median age at first event (years) | |||
| Whole population | 71.02 | 71.12 | 70.96 |
| Only index persons | 70.42 | 69.93 | 70.79 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4572 | 1779 | 2793 |
| Unadjusted period prevalence (%) | 1.24 | 0.77 | 1.54 |
| Median age at first event (years) | 69.06 | 66.41 | 70.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: ILD_ENDPOINTS – Interstitial lung disease endpoints
GWS hits: 11
Loading Relationships table