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Interstitial lung disease

DOID EFO Endpoint Browser

ILD

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J84
  • Hospital discharge: ICD-9 — 515|516
  • Hospital discharge: ICD-8 — 48499|51701
  • Cause of death: ICD-10 — J84
  • Cause of death: ICD-9 — 515|516
  • Cause of death: ICD-8 — 48499|51701

2 out of 7 registries used, show all original rules.

4710

4. Check minimum number of events

None

4710

5. Include endpoints

None

4710

6. Filter based on genotype QC (FinnGen only)

4572

Control definitions (FinnGen only)

Control exclude ILD_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF6
Parent code in ICD-10 J80-J84
Name in latin Alii morbi interstitiales pulmonum

Similar endpoints

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List of similar endpoints to Interstitial lung disease based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 4572 1779 2793
Unadjusted period prevalence (%) 1.24 0.77 1.54
Median age at first event (years) 69.18 66.58 70.84

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: ILD – Interstitial lung disease

GWS hits: 13

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