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Varicose veins

DOID EFO Endpoint Browser PheWeb

I9_VARICVE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I83
  • Hospital discharge: ICD-9 — 454
  • Hospital discharge: ICD-8 — 454
  • Cause of death: ICD-10 — I83
  • Cause of death: ICD-9 — 454
  • Cause of death: ICD-8 — 454

2 out of 7 registries used, show all original rules.

32596

4. Check minimum number of events

None

32596

5. Include endpoints

None

32596

6. Filter based on genotype QC (FinnGen only)

31719

Control definitions (FinnGen only)

Control exclude I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I80-I89
Name in latin Varices membrorum inferiorum

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 363367 277729 83293
Only index persons 301989 235312 66677
Unadjusted period prevalence (%)
Whole population 6.63 7.95 2.33
Only index persons 7.30 8.65 2.55
Median age at first event (years)
Whole population 47.94 46.71 51.83
Only index persons 46.04 44.90 50.03

-FinnGen-

Key figures

All Female Male
Number of individuals 31719 23389 8330
Unadjusted period prevalence (%) 8.69 10.16 4.58
Median age at first event (years) 44.11 41.76 50.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_VARICVE – Varicose veins

GWS hits: 159

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