Embolic stroke

I9_STR_EMBOLIC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I63.1
  • Hospital discharge: ICD-9 4341A
  • Hospital discharge: ICD-8 43400|43499
  • Cause of death: ICD-10 I63.1
  • Cause of death: ICD-9 4341A
  • Cause of death: ICD-8 43400|43499

2 out of 7 registries used, show all original rules.

1538

4. Check minimum number of events

None

1538

5. Include endpoints

None

1538

6. Filter based on genotype QC (FinnGen only)

1484

Control definitions (FinnGen only)

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28696 13054 14985
Only index persons 13155 5750 7405
Unadjusted period prevalence (%)
Whole population 0.40 0.37 0.42
Only index persons 0.25 0.21 0.28
Median age at first event (years)
Whole population 72.78 75.89 70.17
Only index persons 71.63 74.92 69.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1484 463 1021
Unadjusted period prevalence (%) 0.45 0.20 0.56
Median age at first event (years) 69.96 69.64 70.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_STR_EMBOLIC – Embolic stroke

GWS hits: 2

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