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Hypotension

DOID EFO Endpoint Browser PheWeb

I9_HYPOTE

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I95
  • Hospital discharge: ICD-9 — 458
  • Hospital discharge: ICD-8 — 4580
  • Cause of death: ICD-10 — I95
  • Cause of death: ICD-9 — 458
  • Cause of death: ICD-8 — 4580

2 out of 7 registries used, show all original rules.

5092

4. Check minimum number of events

None

5092

5. Include endpoints

None

5092

6. Filter based on genotype QC (FinnGen only)

4924

Control definitions (FinnGen only)

Control exclude I9_OTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I95-I99
Name in latin Hypotensio (arterialis)

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 60503 31758 28282
Only index persons 50400 26909 23491
Unadjusted period prevalence (%)
Whole population 0.85 0.91 0.79
Only index persons 0.95 0.99 0.90
Median age at first event (years)
Whole population 78.05 79.81 76.14
Only index persons 78.34 80.16 76.25

-FinnGen-

Key figures

All Female Male
Number of individuals 4924 2047 2877
Unadjusted period prevalence (%) 1.29 0.89 1.58
Median age at first event (years) 73.94 72.72 74.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_HYPOTE – Hypotension

GWS hits: -

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