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Endocarditis

DOID EFO Endpoint Browser PheWeb

I9_ENDOCARD

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I33, I38, I39*
  • Hospital discharge: ICD-9 — 421|4249|0932A
  • Hospital discharge: ICD-8 — 421
  • Cause of death: ICD-10 — I33, I38, I39*
  • Cause of death: ICD-9 — 421|4249|0932A
  • Cause of death: ICD-8 — 421

2 out of 7 registries used, show all original rules.

1072

4. Check minimum number of events

None

1072

5. Include endpoints

None

1072

6. Filter based on genotype QC (FinnGen only)

1027

Control definitions (FinnGen only)

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11617 4095 7361
Only index persons 8098 2778 5320
Unadjusted period prevalence (%)
Whole population 0.17 0.12 0.21
Only index persons 0.17 0.10 0.20
Median age at first event (years)
Whole population 63.81 67.80 61.53
Only index persons 61.72 64.49 60.28

-FinnGen-

Key figures

All Female Male
Number of individuals 1027 293 734
Unadjusted period prevalence (%) 0.32 0.13 0.40
Median age at first event (years) 62.17 58.98 63.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_ENDOCARD – Endocarditis

GWS hits: 1

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