hypertrophic cardiomyopathy: A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
574 |
4. Check minimum number of eventsNone |
574 |
5. Include endpointsNone |
574 |
6. Filter based on genotype QC (FinnGen only) |
553 |
Control definitions (FinnGen only)
Control exclude
I9_OTHHEART
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
I42
Name in latin
Cardiomyopathia hypertrophica obstructiva
Similar endpoints
↥List of similar endpoints to Cardiomyopathy, Hypertrophic obstructive based on the number of shared cases.
Broader endpoints:
- Cardiomyopathy (excluding other)
- Cardiomyopathy
- Other heart diseases
- Other heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
Narrower endpoints:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 5095 | 2157 | 2870 |
Only index persons | 3542 | 1521 | 2021 |
Unadjusted period prevalence (%) | |||
Whole population | 0.07 | 0.06 | 0.08 |
Only index persons | 0.07 | 0.06 | 0.08 |
Median age at first event (years) | |||
Whole population | 59.89 | 63.64 | 56.99 |
Only index persons | 58.98 | 62.46 | 56.35 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 553 | 220 | 333 |
Unadjusted period prevalence (%) | 0.15 | 0.10 | 0.18 |
Median age at first event (years) | 58.43 | 58.34 | 58.50 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_CARDMYOHYP – Cardiomyopathy, Hypertrophic obstructive
GWS hits: 14
Loading Relationships table