Cardiomyopathies, Secondary/extrinsic

I9_CARDMSEC

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I42.6, I42.7#
  • Hospital discharge: ICD-9 4258A
  • Cause of death: ICD-10 I42.6, I42.7#
  • Cause of death: ICD-9 4258A

2 out of 7 registries used, show all original rules.

184

4. Check minimum number of events

None

184

5. Include endpoints

None

184

6. Filter based on genotype QC (FinnGen only)

181

Control definitions (FinnGen only)

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4781 746 3926
Only index persons 2094 381 1713
Unadjusted period prevalence (%)
Whole population 0.10 0.02 0.11
Only index persons 0.06 0.01 0.07
Median age at first event (years)
Whole population 56.51 59.10 55.87
Only index persons 58.60 60.45 58.19

-FinnGen-

Key figures

All Female Male
Number of individuals 181 54 127
Unadjusted period prevalence (%) 0.06 0.02 0.07
Median age at first event (years) 59.92 54.33 62.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_CARDMSEC – Cardiomyopathies, Secondary/extrinsic

GWS hits: 2

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