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Coronary artery bypass grafting

DOID EFO Endpoint Browser PheWeb

I9_CABG

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes — ^FNA|^FNB|^FNC|^FND|^FNE
  • Operations: Finnish Hospital League codes — ^5311$|^5312$|^5313$|^5314$|^5315$
  • Operations: Heart Patient codes v1 — ^11|^25$
  • Operations: Heart Patient codes v2 — ^AA1|^AA2|^AA3|^AAX

1 out of 7 registries used, show all original rules.

11957

4. Check minimum number of events

None

11957

5. Include endpoints

None

11957

6. Filter based on genotype QC (FinnGen only)

11582

Control definitions (FinnGen only)

Control exclude I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF10

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 89489 20741 67703
Only index persons 72151 16822 55329
Unadjusted period prevalence (%)
Whole population 1.58 0.59 1.89
Only index persons 1.76 0.62 2.11
Median age at first event (years)
Whole population 66.57 70.38 65.38
Only index persons 66.26 70.10 65.10

-FinnGen-

Key figures

All Female Male
Number of individuals 11582 1888 9694
Unadjusted period prevalence (%) 4.60 0.82 5.33
Median age at first event (years) 64.94 67.53 64.44

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_CABG – Coronary artery bypass grafting

GWS hits: 74

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