atherosclerosis: Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
16730 |
4. Check minimum number of eventsNone |
16730 |
5. Include endpointsNone |
16730 |
6. Filter based on genotype QC (FinnGen only) |
16243 |
Control definitions (FinnGen only)
Control exclude
I9_DOAAC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I70-I79
Name in latin
Atherosclerosis
Similar endpoints
↥List of similar endpoints to Atherosclerosis, excluding cerebral, coronary and PAD based on the number of shared cases.
Broader endpoints:
- Diseases of arteries, arterioles and capillaries (FINNGEN)
- Diseases of arteries, arterioles and capillaries
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Narrower endpoints:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 196160 | 81610 | 110955 |
Only index persons | 123818 | 53401 | 70417 |
Unadjusted period prevalence (%) | |||
Whole population | 2.79 | 2.34 | 3.10 |
Only index persons | 2.38 | 1.96 | 2.69 |
Median age at first event (years) | |||
Whole population | 72.94 | 77.00 | 70.02 |
Only index persons | 72.49 | 76.43 | 69.50 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 16243 | 4769 | 11474 |
Unadjusted period prevalence (%) | 5.07 | 2.07 | 6.31 |
Median age at first event (years) | 69.39 | 69.85 | 69.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_ATHSCLE – Atherosclerosis, excluding cerebral, coronary and PAD
GWS hits: 18
Loading Relationships table