Arterial embolism and thrombosis of lower extremity artery

I9_ARTEMBTHRLOW

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I74.3
  • Hospital discharge: ICD-9 4442A
  • Cause of death: ICD-10 I74.3
  • Cause of death: ICD-9 4442A

2 out of 7 registries used, show all original rules.

1103

4. Check minimum number of events

None

1103

5. Include endpoints

None

1103

6. Filter based on genotype QC (FinnGen only)

1076

Control definitions (FinnGen only)

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I74
Name in latin Embolia arteriarum membrorum inferiorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15872 7887 7734
Only index persons 9951 4973 4978
Unadjusted period prevalence (%)
Whole population 0.22 0.23 0.22
Only index persons 0.19 0.18 0.19
Median age at first event (years)
Whole population 75.44 80.10 70.77
Only index persons 74.25 79.43 69.07

-FinnGen-

Key figures

All Female Male
Number of individuals 1076 405 671
Unadjusted period prevalence (%) 0.30 0.18 0.37
Median age at first event (years) 70.18 70.40 70.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_ARTEMBTHRLOW – Arterial embolism and thrombosis of lower extremity artery

GWS hits: 1

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