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Aortic aneurysm

DOID EFO Endpoint Browser PheWeb

I9_AORTANEUR

aortic aneurysm: A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

8252

4. Check minimum number of events

None

8252

5. Include endpoints

8361

6. Filter based on genotype QC (FinnGen only)

8124

Control definitions (FinnGen only)

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 65409 13862 50372
Only index persons 46805 10214 36591
Unadjusted period prevalence (%)
Whole population 1.19 0.40 1.41
Only index persons 1.17 0.38 1.40
Median age at first event (years)
Whole population 70.61 73.53 69.81
Only index persons 70.20 72.79 69.48

-FinnGen-

Key figures

All Female Male
Number of individuals 8124 1234 6890
Unadjusted period prevalence (%) 3.30 0.54 3.79
Median age at first event (years) 69.80 69.09 69.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_AORTANEUR – Aortic aneurysm

GWS hits: 24

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