Retinal detachment with retinal break

H7_RETINALDETACHBREAK

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H33.0
  • Hospital discharge: ICD-9 3610
  • Hospital discharge: ICD-8 37602
  • Cause of death: ICD-10 H33.0
  • Cause of death: ICD-9 3610
  • Cause of death: ICD-8 37602

2 out of 7 registries used, show all original rules.

4148

4. Check minimum number of events

None

4148

5. Include endpoints

None

4148

6. Filter based on genotype QC (FinnGen only)

4024

Control definitions (FinnGen only)

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H33
Name in latin Amotio/ablatio retinae cum ruptura

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38578 16940 21396
Only index persons 34930 15487 19443
Unadjusted period prevalence (%)
Whole population 0.55 0.49 0.60
Only index persons 0.67 0.57 0.74
Median age at first event (years)
Whole population 61.36 62.21 60.64
Only index persons 60.64 61.44 60.01

-FinnGen-

Key figures

All Female Male
Number of individuals 4024 1705 2319
Unadjusted period prevalence (%) 1.05 0.74 1.28
Median age at first event (years) 60.32 58.81 61.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H7_RETINALDETACHBREAK – Retinal detachment with retinal break

GWS hits: 2

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