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Pterygium

DOID EFO Endpoint Browser PheWeb

H7_PTERYGIUM

pterygium: A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H11.0
  • Hospital discharge: ICD-9 — 3724
  • Hospital discharge: ICD-8 — 372
  • Cause of death: ICD-10 — H11.0
  • Cause of death: ICD-9 — 3724
  • Cause of death: ICD-8 — 372

2 out of 7 registries used, show all original rules.

821

4. Check minimum number of events

None

821

5. Include endpoints

None

821

6. Filter based on genotype QC (FinnGen only)

756

Control definitions (FinnGen only)

Control exclude H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Pterygium

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10019 3736 6008
Only index persons 8003 3281 4722
Unadjusted period prevalence (%)
Whole population 0.15 0.11 0.17
Only index persons 0.16 0.12 0.18
Median age at first event (years)
Whole population 59.38 58.25 60.83
Only index persons 58.52 56.95 59.61

-FinnGen-

Key figures

All Female Male
Number of individuals 756 275 481
Unadjusted period prevalence (%) 0.21 0.12 0.26
Median age at first event (years) 60.53 56.46 62.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H7_PTERYGIUM – Pterygium

GWS hits: 1

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