Papilloedema, unspecified

H7_PAPILLOEDEMA

optic papillitis: Swelling of the optic disk, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause optic atrophy and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H47.1
  • Hospital discharge: ICD-9 3770
  • Hospital discharge: ICD-8 37791
  • Cause of death: ICD-10 H47.1
  • Cause of death: ICD-9 3770
  • Cause of death: ICD-8 37791

2 out of 7 registries used, show all original rules.

637

4. Check minimum number of events

None

637

5. Include endpoints

None

637

6. Filter based on genotype QC (FinnGen only)

615

Control definitions (FinnGen only)

Control exclude H7_OPTNERVE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H47
Name in latin Oedema papillae non specificatum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5484 3197 2258
Only index persons 4991 2970 2021
Unadjusted period prevalence (%)
Whole population 0.08 0.09 0.06
Only index persons 0.10 0.11 0.08
Median age at first event (years)
Whole population 42.25 38.70 47.19
Only index persons 41.63 37.90 47.11

-FinnGen-

Key figures

All Female Male
Number of individuals 615 389 226
Unadjusted period prevalence (%) 0.15 0.17 0.12
Median age at first event (years) 46.61 41.22 55.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H7_PAPILLOEDEMA – Papilloedema, unspecified

GWS hits: 3

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