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conjunctival degenerations and deposits

DOID EFO Endpoint Browser PheWeb

H7_CONJUNCTDEGDEPOT

pinguecula: A yellowish thickened lesion on the conjunctiva near the cornea representing a benign degenerative change in the conjunctiva caused by the leakage and deposition of certain blood proteins through the permeable capillaries near the limbus.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H11.1
  • Hospital discharge: ICD-9 — 3725
  • Cause of death: ICD-10 — H11.1
  • Cause of death: ICD-9 — 3725

2 out of 7 registries used, show all original rules.

642

4. Check minimum number of events

None

642

5. Include endpoints

None

642

6. Filter based on genotype QC (FinnGen only)

613

Control definitions (FinnGen only)

Control exclude H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Degenerationes et deposita conjunctivae

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5600 3529 2024
Only index persons 5007 3200 1807
Unadjusted period prevalence (%)
Whole population 0.08 0.10 0.06
Only index persons 0.10 0.12 0.07
Median age at first event (years)
Whole population 53.72 53.94 53.55
Only index persons 52.74 52.84 52.55

-FinnGen-

Key figures

All Female Male
Number of individuals 613 389 224
Unadjusted period prevalence (%) 0.15 0.17 0.12
Median age at first event (years) 53.41 51.69 56.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H7_CONJUNCTDEGDEPOT – conjunctival degenerations and deposits

GWS hits: -

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