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Other cataract

DOID EFO Endpoint Browser PheWeb

H7_CATARACTOTHER

cataract: Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H26
  • Hospital discharge: ICD-9 — 366
  • Hospital discharge: ICD-8 — 374
  • Hospital discharge: excluded ICD-9 — 3661
  • Hospital discharge: excluded ICD-8 — 37403
  • Cause of death: ICD-10 — H26
  • Cause of death: ICD-9 — 366
  • Cause of death: ICD-8 — 374
  • Cause of death: excluded ICD-9 — 3661
  • Cause of death: excluded ICD-8 — 37403

2 out of 7 registries used, show all original rules.

20030

4. Check minimum number of events

None

20030

5. Include endpoints

None

20030

6. Filter based on genotype QC (FinnGen only)

19401

Control definitions (FinnGen only)

Control exclude H7_LENS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H25-H28
Name in latin Alia cataracta

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 211033 132564 76995
Only index persons 178709 114677 64032
Unadjusted period prevalence (%)
Whole population 3.18 3.80 2.15
Only index persons 3.58 4.22 2.44
Median age at first event (years)
Whole population 72.07 75.11 66.94
Only index persons 72.12 75.22 66.58

-FinnGen-

Key figures

All Female Male
Number of individuals 19401 11111 8290
Unadjusted period prevalence (%) 4.71 4.83 4.56
Median age at first event (years) 69.50 70.40 68.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H7_CATARACTOTHER – Other cataract

GWS hits: 14

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