Aphakia

H7_APHAKIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H27.0
  • Hospital discharge: ICD-9 3793A
  • Hospital discharge: ICD-8 37872
  • Cause of death: ICD-10 H27.0
  • Cause of death: ICD-9 3793A
  • Cause of death: ICD-8 37872

2 out of 7 registries used, show all original rules.

535

4. Check minimum number of events

None

535

5. Include endpoints

None

535

6. Filter based on genotype QC (FinnGen only)

510

Control definitions (FinnGen only)

Control exclude H7_LENS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H27
Name in latin Aphakia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10286 5262 4814
Only index persons 5128 2468 2660
Unadjusted period prevalence (%)
Whole population 0.14 0.15 0.13
Only index persons 0.10 0.09 0.10
Median age at first event (years)
Whole population 63.75 67.32 59.82
Only index persons 53.87 59.58 48.57

-FinnGen-

Key figures

All Female Male
Number of individuals 510 185 325
Unadjusted period prevalence (%) 0.14 0.08 0.18
Median age at first event (years) 55.24 54.14 55.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H7_APHAKIA – Aphakia

GWS hits: 2

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