nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
9633 |
4. Check minimum number of eventsNone |
9633 |
5. Include endpoints |
30939 |
6. Filter based on genotype QC (FinnGen only) |
29982 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Other neurological diseases
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 330757 | 170452 | 157069 |
| Only index persons | 258723 | 137531 | 121192 |
| Unadjusted period prevalence (%) | |||
| Whole population | 4.63 | 4.88 | 4.39 |
| Only index persons | 4.85 | 5.06 | 4.63 |
| Median age at first event (years) | |||
| Whole population | 67.23 | 68.92 | 65.36 |
| Only index persons | 65.53 | 66.91 | 63.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 29982 | 14949 | 15033 |
| Unadjusted period prevalence (%) | 7.38 | 6.49 | 8.27 |
| Median age at first event (years) | 63.37 | 60.92 | 65.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: G6_OTHNEU – Other neurological diseases
GWS hits: 2
Loading Relationships table