Other demyelinating diseases of the central nervous system

G6_OTHDEMYEL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G37
  • Hospital discharge: ICD-9 341[1-9]
  • Hospital discharge: ICD-8 3410[2-9]
  • Cause of death: ICD-10 G37
  • Cause of death: ICD-9 341[1-9]
  • Cause of death: ICD-8 3410[2-9]

2 out of 7 registries used, show all original rules.

1191

4. Check minimum number of events

None

1191

5. Include endpoints

None

1191

6. Filter based on genotype QC (FinnGen only)

1149

Control definitions (FinnGen only)

Control exclude G6_DEMYEL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G35-G37
Name in latin Alii morbi demyelinantes systematis nervosi centralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8543 5445 3043
Only index persons 7717 5057 2660
Unadjusted period prevalence (%)
Whole population 0.13 0.16 0.09
Only index persons 0.16 0.19 0.10
Median age at first event (years)
Whole population 39.82 38.63 41.86
Only index persons 39.14 38.08 41.15

-FinnGen-

Key figures

All Female Male
Number of individuals 1149 845 304
Unadjusted period prevalence (%) 0.31 0.37 0.17
Median age at first event (years) 39.67 38.18 43.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_OTHDEMYEL – Other demyelinating diseases of the central nervous system

GWS hits: 1

loading spinner Loading Relationships table